Once you install App-V Deployment Kit for Office 2010 and enable proxies on Office package, this’ll take over any integration with SharePoint and other Office products before 2010. When you launch a SharePoint site, virtualOWSuppmanager.exe launches and this process will also launch virtualOWSSUPPHOST.exe. These’re the two processes that control integration with App-V and virtualized Office 2010. What happens is that there’s a delay between Internet Explorer launching and detection to launch virtualOWSuppManager. We can try minimizing this latency by performing following embedded changes in the Office 2010 package. The best part is that we don’t need to re-sequence the package, we can just open the package for upgrade and add a script to the OSD file for VrtualOWSsuppmanager.