During sequencing process of Office 2010 on Windows Vista SP1 or SP2 using App-V 4.6 sequencer you may get following error (see pic). This can occur because of an issue between VC++ Redistributables used in Vista and the way App-V 4.6 Sequencer handles them. Also note that this issue only occurs with Vista. If you're using Win7 then you shouldn't run into this issue.
Unfortunately deleting & replacing files doesn't work but resolution is actually very simple. To avoid this issue, during sequencing only launch Word and Excel, then configure Windows Update settings and toolbars as wanted. Don't launch PowerPoint and Access at this point. Once the sequence is complete you can stream down package to Vista machines and they should launch with no problems.
Here're some links for Office 2010 Guides and Deployment kits:
- Prescriptive guidance for sequencing Office 2010 in Microsoft App-V
- Microsoft Office 2010 Deployment Kit for App-V