Ryan J Lowe’s has released LITBox 2.0. LITBox is basically a few modifications of Thickbox made into a Prototype class based off of the Scriptaculous. Probably the biggest advantage of the LITBox, is that it is a lightbox written into a class. This gives it the ability to open multiple instances of the LITBox and be able to control each one with unique settings and controls”.
LITBox has a pretty good list of features that I built into it (thanks mainly to script.aculo.us) that allow you to manipulate size, opacity, and type as well as the ability to choose whether the window can be draggable or resizable.