Google now has a new specialized search engine for searching Google Profiles. The new profiles search engine has a better interface than the regular Google Profiles search feature. It's integrated with Google Search and it shows additional links from people's profiles.
This feature is not yet enabled in the Google.com interface, and to search Google Profiles you can do this by adding &tbs=prfl:1 to a Google Search URL.
Here's an example:
Google could use the data from user profiles to provide advanced search features like restricting profiles to people who lived in Chicago, attended Long Island University and are interested in sports.
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[Thanks, Alex, Source]