Microsoft in an Knowledge base article KB2575077, confirmed an issue impacting customers running Windows 7 and Windows Server 2008 R2, in which the platform can freeze when memory usage is high.
According to the Microsoft,
A computer that is running Windows Server 2008 R2 or Windows 7 randomly stops responding. The issue typically occurs when the memory usage is high and when the memory manager performs frequent paging in and paging out actions.
Note You can use the Memory\Page Faults/sec performance counter to track the paging in and paging out frequency.
Microsoft says that the "issue occurs because of a deadlock situation in the Microsoft Filesystem Filter Manager (Fltmgr.sys)."
To resolve this issue, the Redmond company has made available a hotfix to those customers that have come across the issue described in this article.
The fix is available through Microsoft Support, but customers should only download and deploy it if they are indeed experiencing issues with their copy of Windows 7 SP1, Windows Server 2008 R2 SP1 or earlier.
You can download the hotfix here.